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胶原酶(collagenase)具有独特的消化天然胶原蛋白和变性胶原的能力,为一有效的清创、愈合、脱痂药物。上海医药工业研究院于1980年试制成外用油膏(含250单位/g),通过工艺研究、实验性烫伤的疗效以及毒性试验后,由上海市卫生局于1981～83年安排上海市二、瑞金、长海、中山、长征、浦东中心、闵行工农、华山、虹口、中心、市六等医院进行临床试验,用于皮肤慢性溃疡及褥疮168例,有效率84.5％;灼伤50例,有效44例(清疮脱痂,加速愈合)。证实本油膏对坏死组织的脱落、肉芽组织的形成以及促进上皮组织的生长均有作
Collagenase (collagenase) has a unique ability to digest natural collagen and denatured collagen, as an effective debridement, healing, scabs drugs. Shanghai Institute of Pharmaceutical Industry trial in 1980 made into a topical ointment (including 250 units / g), through the process of research, the efficacy of experimental scald and toxicity test by the Shanghai Municipal Health Bureau in 1981 to 83 years to arrange Shanghai II Clinical trial of Ruijin, Changhai, Zhongshan, Long March, Pudong Center, Minhang Workers and Peasants, Huashan, Hongkou, Center and City Sixth Hospital for 168 cases of chronic skin ulcers and pressure ulcers with an effective rate of 84.5%; burns of 50 cases and effective 44 Case (clear sore scab, accelerate healing). Confirmed the ointment of necrotic tissue shedding, granulation tissue formation and promote epithelial tissue growth are