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许多研究表明,应用环孢菌素加强的松较硫唑嘌呤加强的松对行肾移植病人的成活率高。环孢菌素有对肾脏及肝脏的毒性效应、高血压、齿龈增生及多毛症等副作用。作者报告11例接受肾移植的儿童应用环孢菌素加强的松引起面部容貌改变。
Many studies have shown that the application of cyclosporin-enhanced pine than azathioprine-enhanced pine on the line of renal transplant patients with high survival rate. Cyclosporine has toxic effects on the kidneys and liver, high blood pressure, gingival hyperplasia and hirsutism and other side effects. The authors report that cyclosporin-boosted pine in 11 children undergoing kidney transplantation caused changes in facial appearance.