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本文报告45名慢阻肺患者,40名肺心病患者及252名健康人血清Cu、Zn含量及Cu/Zn比值。结果提示Cu含量及Cu/Zn比值顺序如下:肺心病>COPD>健康者,Zn含量则肺心病50mmHg的肺心病人比较,Cu、Cu/Zn前者高于后者,Zn则前者低于后者,且有非常显著的统计学差异。对Cu、Zn及Cu/Zn变化病理生理学机制加以讨论。 血微量元素含量的研究近年来取得长足进步,尤其是铜锌含量尤为人们注意。不仅有治疗上的价值,而且有助于疾病的诊断,预后。国内对肺癌,白血病,肝脏病、冠心病方面的研究已有报告,对慢阻肺、肺心病研究极少,本文在这个领域作了初步探讨。
This article reports the serum Cu, Zn content and Cu / Zn ratio of 45 COPD patients, 40 pulmonary heart disease patients and 252 healthy controls. The results suggest that Cu content and Cu / Zn ratio in the following order: pulmonary heart disease> COPD> healthy, Zn content of pulmonary heart disease 50mmHg pulmonary heart disease patients, Cu, Cu / Zn former was higher than the latter, while Zn was lower than the former, and there is a very significant statistical difference. The pathophysiological mechanisms of Cu, Zn and Cu / Zn changes were discussed. In recent years, great progress has been made in the study of trace elements in blood, especially copper and zinc. Not only has the therapeutic value, but also contributes to the diagnosis and prognosis of the disease. Domestic research on lung cancer, leukemia, liver disease and coronary heart disease has been reported. There is very little research on COPD and pulmonary heart disease. This article makes a preliminary study in this field.