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本文总结了我院儿科1975—1985年间15岁以下小儿中枢神经系统白病(CNL)32例,占同期收治急性自血病177例的18.1%·CNL 可并发于白血病的任何时期,本组56.3%发生于白血病确诊后2个月内。本病起病缓慢,症状体征不明显,诊断有一定困难,早期腰穿检查脑脊液,可提高诊断率。我院于1979年始采用三炎杉酯类药物鞘内注射治疗,疗效满意,尤其对急性非淋巴细胞白血病(ANLL)合并CNL 的效果更佳,该药具有副作用小、用药间隔时间长、复发后再用仍有效等优点,故我们认为三尖杉酯类药物是治疗CNL 的一种新药,值得推广。
This article summarizes our pediatric pediatric in 1975-1985 15 years of age children with central nervous system disease (CNL) in 32 cases, accounting for the same period of acute leukemia in 177 cases of 18.1% · CNL can be complicated by any period of leukemia in this group of 56.3 % Occurred within 2 months after the diagnosis of leukemia. Slow onset of the disease, symptoms and signs are not obvious, the diagnosis of some difficulties, early lumbar puncture check cerebrospinal fluid, can improve the diagnostic rate. In our hospital in the beginning of 1979 with three infusions intrathecal injection therapy, with satisfactory results, especially for acute non-lymphocytic leukemia (ANLL) combined with CNL better effect, the drug has the side effects of small, long interval between drugs, recurrence Re-use is still valid, etc. Therefore, we believe that harringtonine is a new drug for the treatment of CNL, it is worth promoting.