经临床观察证明,多菌灵A治疗银屑病有效。为了解其作用机理,我们采用两种动物实验模型——雌激素周期阴道上皮和鼠尾鳞片表皮进行研究。结果表明:多菌灵A可抑制表皮细胞分裂,从而使银屑病表皮的增生过快得以纠正,但对颗粒层表皮细胞形成无促进作用。 Clinical observations show that carbendazim A is effective in the treatment of psoriasis. To understand its mechanism of action, we used two animal models, the estrogen cycle vaginal epithelium and rat tail scale epidermis. The results showed that carbendazim can inhibit the epidermal cell division, so that the psoriatic epidermis hyperplasia can be corrected quickly, but it has no promoting effect on the formation of epidermal cells in the granular layer.