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目的探讨饮水氟含量及尿氟、血清氟与氟斑牙患病率的相关性。方法选择河南省林州市和登封市作为调查点,对6~13岁在校儿童(林州市235名、登封市214名)的尿氟、血清氟含量、氟斑牙患病率及家庭饮水氟含量实施调查,比较儿童尿氟、血清氟含量、氟斑牙患病率及家庭饮水氟含量等情况,分析家庭饮水氟含量及儿童尿氟、血清氟含量与氟斑牙患病率的相关性。结果林州市的家庭饮水氟含量及儿童尿氟、血清氟含量均高于登封市,差异有统计学意义(均P<0.05);林州儿童氟斑牙患病率为83.83%(197/235),高于登封的4.67%(10/214),差异有统计学意义(P<0.05);经Spearman相关性分析,饮水氟含量及儿童尿氟、血清氟含量与氟斑牙患病率间呈显著正相关(P<0.05)。结论饮水氟含量及尿氟、血清氟与氟斑牙患病率密切相关,对其进行有效监测有助于防治氟斑牙。
Objective To investigate the relationship between fluoride content in drinking water and urinary fluoride, serum fluoride and the prevalence of dental fluorosis. Methods Linzhou City and Dengfeng City of Henan Province were selected as the investigation points. The prevalence of urinary fluoride, serum fluoride and dental fluorosis in 6-13-year-old children (235 in Linzhou City and 214 in Dengfeng City) And fluorine content in drinking water were investigated in children. Urinary fluoride, serum fluorine content, prevalence of dental fluorosis and fluorine content in drinking water were compared between the two groups. The fluoride content in drinking water, urinary fluoride, serum fluoride and dental fluorosis Rate of relevance. Results The fluoride content, urinary fluoride and serum fluoride in children in Linzhou City were higher than those in Dengfeng City (both P <0.05). The prevalence of dental fluorosis in Linzhou children was 83.83% (197 / 235), which was higher than that of Dengfeng (4.67%, 10/214) (P <0.05). According to Spearman correlation analysis, the fluoride content in drinking water, urine fluoride in children, serum fluoride content and dental fluorosis There was a significant positive correlation between disease rates (P <0.05). Conclusion The fluoride content, urinary fluoride and serum fluorine in drinking water are closely related to the prevalence of dental fluorosis. Effective monitoring of fluoride content in drinking water can help prevent dental fluorosis.