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作者比较了新近在4所Dallas医院治疗的12例多毛细胞白血病(HCL)与15例慢性淋巴细胞白血病(LCL)的感染率,并复习了173例文献报告的HCL病例。证明本病患者易合并由细胞介导免疫控制的感染。方法:根据脾肿大和血液、骨髓活检标本中存在典型多毛细胞的贫血诊断HCL。根据出现无法解释的淋巴细胞不断增加(≥15000/mm~3)并伴有骨髓淋巴细胞浸润(≥30%)诊断CLL。
The authors compared the infection rates of 12 cases of hairy cell leukemia (HCL) and 15 cases of chronic lymphocytic leukemia (LCL) recently treated in 4 Dallas hospitals and reviewed 173 cases of HCL reported in the literature. Proves that patients with this disease are susceptible to infection mediated by cell-mediated immunity. Methods: HCL was diagnosed according to the presence of typical hairy cell anemia in splenomegaly and blood and bone marrow biopsy specimens. CLL is diagnosed on the basis of an increasing number of unexplained lymphocytes (≥15000 / mm 3) with bone marrow lymphocytic infiltrates (≥30%).