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目的 比较心肌肌钙蛋白Ⅰ (cTnⅠ )与常用的急性心肌梗死 (AMI)诊断标志物肌酸激酶同功酶(CK MB)的临床应用价值。方法 采用 31例AMI病人的同一血标本 ,同时检测cTnⅠ和CK MB ,然后进行两者比较。结果 cTnⅠ对急性心肌梗死诊断的敏感性和特异性高于CK MB ,其敏感性分别为 96 7%和80 6 % ,P <0 0 5 ;特异性分别为 94 4 %和 77 7% ,P <0 0 5。结论 心肌肌钙蛋白Ⅰ对于AMI诊断具有较高的敏感性和特异性 ,是一种心肌损伤的特异性标志物 ,具有较好的临床使用价值。
Objective To compare the clinical value of cardiac troponin Ⅰ (cTn Ⅰ) with common acute myocardial infarction (AMI) diagnostic marker creatine kinase isoenzyme (CK MB). Methods 31 cases of AMI patients with the same blood samples, both cTn Ⅰ and CK MB, and then compare the two. Results The sensitivity and specificity of cTnⅠ for the diagnosis of acute myocardial infarction were higher than that of CK MB. The sensitivity of cTnⅠ was 96.7% and 80.6% respectively, P <0 05; the specificity was 94.4% and 77.7% <0 0 5. Conclusions Cardiac troponin Ⅰ is highly sensitive and specific for the diagnosis of AMI. It is a specific marker of myocardial injury and has good clinical value.