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目的分析以检测疟原虫乳酸脱氢酶的疟疾快速检测试剂卡与疟原虫镜检及疟疾患者乳酸脱氢酶检测进行比较观察。方法对2015~2016年在加纳务工返乡人员以疟原虫镜检阳性住院治疗前的患者作为主要观察对象,同时进行快速疟原虫检测试剂卡检测(胶体金法)及患者乳酸脱氢酶检测,疟疾阳性患者按照四种疟原虫种类分组统计分析比较。结果疟疾观察患者共144例,其中镜检阳性患者共142例和2例临床症状明显血检阴性患者,镜检阳性率为98.61%(142/144)。恶性疟108例,间日疟、三日疟和卵形疟分别为9例、1例和24例。快速疟原虫检测试剂检测总体阳性率为95.14%(137/144),两种方法的统计学检验差异无统计学意义(P>0.05)。乳酸脱氢酶增高的患者占44.44%(64/144),与血检方法比较统计学检验差异有高度统计学意义(P<0.01)。结论该快速疟原虫检测试剂对疟原虫镜检技术掌握不熟练的医疗机构是一种较好的辅助检测试剂。而临床检验乳酸脱氢酶增高患者作为判断为疟疾患者存在较大的差异。
Objective To compare the detection of lactate dehydrogenase (LDH) in malaria parasite and malaria patients by using the rapid malaria detection kit of malaria parasite lactate dehydrogenase. Methods The patients who returned to work in Ghana from 2015 to 2016 before positive hospitalization with Plasmodium as the main object of observation were treated with rapid Plasmodium test card (colloidal gold assay) and lactate dehydrogenase (LDH) Malaria-positive patients were grouped by statistical analysis of four species of Plasmodium. Results A total of 144 malaria patients were observed, of which 142 were positive for microscopic examination and 2 were negative for clinical examination. The positive rate of microscopic examination was 98.61% (142/144). 108 cases of Plasmodium falciparum, 9 cases of Plasmodium vivax, 3 days Malaria and oval malaria, 1 case and 24 cases. The overall positive rate of rapid Plasmodium detection reagent was 95.14% (137/144). There was no significant difference between the two methods (P> 0.05). The patients with elevated lactate dehydrogenase accounted for 44.44% (64/144). There was a statistically significant difference between the two groups (P <0.01). Conclusion The rapid Plasmodium test reagent is a good assistant test reagent for unskilled medical institutions for Plasmodium test. However, patients with elevated lactate dehydrogenase have a greater discrepancy in judging malaria patients.