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目的:了解我院住院肾内科抗菌药物使用情况,为临床抗菌药物的合理使用提供参考。方法:随机抽取我院住院肾内科2010年12月份~2011年4月份归档病历30份,对抗菌药物使用的品种、药品用药频度(DDDs)和药物利用指数(DUI)、联合用药、用药合理性进行分析评价。结果:30份病案中有20份病案使用了抗菌药物,使用率66.67%,抗菌药物品种达13种,主要是头孢菌素及非典型β内酰胺类10种、喹诺酮类1种、青霉素类1种、大环内酯类1种;用药过程中,单用占80%、二联占15%、三联占5%;DDDs排序前3位的是头孢美唑、克拉霉素、阿莫西林,所用的抗菌药物除克拉霉素、头孢呋辛DUI>1外,其余均DUI≤1。结论:我院住院肾内科抗菌药物使用基本合理。
OBJECTIVE: To understand the use of antimicrobial agents in our hospital for nephrology and to provide a reference for the rational use of clinical antimicrobial agents. Methods: A total of 30 medical records filed in our hospital from December 2010 to April 2011 were randomly collected. The varieties, drug use frequency (DDDs), drug use index (DUI), combined medication and reasonable medication Sex analysis and evaluation. Results: In 30 medical cases, 20 cases were used antibacterial drugs, with a utilization rate of 66.67% and 13 kinds of antibacterial drugs, including cephalosporins and 10 atypical β-lactams, 1 quinolone, 1 penicillin 1 species of macrolide; drug use alone accounted for 80%, two together accounted for 15%, triple accounted for 5%; DDDs sort the top three are cefmetazole, clarithromycin, amoxicillin, Antibacterial drugs used in addition to clarithromycin, cefuroxime DUI> 1, the rest are DUI ≤ 1. Conclusions: The use of antimicrobial agents in our hospital is basically reasonable.