多发性原发性肺癌(Multiple primary lungcancer,MPLC)系指同一患者肺部同时和/或先后发生两个或两个以上的原发性癌瘤。自1924年Beyreuther首次报告双侧原发性肺癌以来,迄今已报告250例以上。其发病率占原发性肺癌的0.09～3.55%。MPLC的临床重要性在于:①由于近年来原发性肺癌发病率明显增高,以及手术后长期 Multiple primary lung cancer (MPLC) refers to the occurrence of two or more primary cancers simultaneously and/or one after another in the same patient’s lungs. Since Beyreuther first reported bilateral primary lung cancer in 1924, more than 250 cases have been reported so far. Its incidence accounts for 0.09-3.55% of primary lung cancer. The clinical significance of MPLC lies in: 1 Due to the marked increase in the incidence of primary lung cancer in recent years, and long-term after surgery