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Strathclyde大学药学系和Glasgo w皇家医院的一个研究小组发明了解决癌症化疗中的毒性问题的新方法。新方法的依据是,癌瘤中血管生长异常。动物试验和人体研究表明上述方法是有希望的。肿瘤产生的化学物质刺激血管迅速向肿瘤内生长,并为肿瘤提供营养与氧气。但是,新生血管壁的肌肉结构与为正常器官供血的血管不同。在应用药物减少到达器官的血流时。由于使动脉壁肌肉收缩而引起动脉收缩,进入肿瘤的血流不受影响,因此增加了与正常器官有关的血流。 Neville Willmott等人用人白蛋白微型球包裹抗癌药阿霉素(adriamycin).装有药
A team of researchers from the Faculty of Pharmacy at Strathclyde University and the Glasgow W Royal Hospital invented a new method for solving the toxic problems in cancer chemotherapy. The new method is based on the abnormal growth of blood vessels in cancerous tumors. Animal experiments and human studies have shown that the above method is promising. The chemicals produced by the tumor stimulate the blood vessels to rapidly grow into the tumor and provide nutrients and oxygen to the tumor. However, the muscle structure of the neovascular wall differs from that of blood vessels supplying normal organs. When applying medications to reduce blood flow to organs. Due to contraction of the arteries by contracting the arterial wall muscles, the flow of blood into the tumor is not affected, thus increasing the blood flow associated with normal organs. Neville Willmott et al. used human albumin microspheres to coat the anticancer drug adriamycin.