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目的:了解食品、公共场所从业人员乙肝五项及丙氨酸氨基转移酶(ALT)异常情况,为乙肝防治提供科学依据。方法:用酶联免疫吸附试验(ELISA)进行乙肝五项标志物检测,用赖氏法测定ALT,并进行分析比较。结果:在2006年-2009年共检测8217人,乙肝感染率从2006年9.47%下降至2009年6.03%,在17岁~25岁、26岁~40岁、41岁~55岁三年龄段感染率分别为:5.21%、6.91%、10.60%。在大三阳(HBsAg、HBeAg和HBcAb均阳性)中,ALT异常率为5.45%,在小三阳(HBsAg、HBeAb、HBcAb均阳性)为4.32%,没有显著性差异,χ2=0.37,P>0.05。结论:从业人员乙肝感染率呈下降趋势,但仍维持在较高水平,需进一步预防控制。
OBJECTIVE: To understand the abnormalities of hepatitis B and alanine aminotransferase (ALT) in food and public places and provide a scientific basis for prevention and treatment of hepatitis B. Methods: Enzyme-linked immunosorbent assay (ELISA) was used to detect five markers of hepatitis B, ALT was determined by Lai’s method and analyzed. Results: A total of 8217 people were tested in 2006-2009, the infection rate of hepatitis B dropped from 9.47% in 2006 to 6.03% in 2009, and the infection rate was in the third age group between 17 years old and 25 years old, 26 years old and 40 years old, 41 years old and 55 years old Rates were: 5.21%, 6.91%, 10.60%. The abnormal rate of ALT was 5.45% in the three positives (positive in HBsAg, HBeAg and HBcAb), 4.32% in the small three positives (positive in HBsAg, HBeAb and HBcAb), χ2 = 0.37, P> 0.05 . Conclusion: The infection rate of hepatitis B in employment is declining, but it is still at a high level, and further prevention and control is needed.