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色甘酸二钠(DSCG)能够抑制肥大细胞的脱颗粒现象,即阻止化学介质的释放,从而具有抗变态反应作用。作者报告1973年11月—1974年3月期间,应用DSCG治疗35例鼻变态反应患者的临床结果。鼻变态反应诊断标准可分三类:Ⅰ型(变态反应性鼻炎):皮内试验及鼻诱发试验均阳性,能确定变应原;Ⅱ型(疑为变态反应性鼻炎):皮内试验阳性而诱发试验阴性;Ⅲ型(所谓血管运动性鼻炎):皮内试验阴性。(三型患者均具有喷嚏发作、水样鼻涕及鼻阻塞等症状)。35例中Ⅰ型23例、Ⅱ型5例、Ⅲ型7例。用药方法:将DSCG胶囊(含DSCG及乳糖各20毫克)放入鼻用喷雾器内,分别喷入双鼻腔,每日4次,连续
Disodium cromoglycate (DSCG) inhibits the degranulation of mast cells, ie prevents the release of chemical mediators and thus has an anti-allergic effect. The authors report the clinical results of 35 patients with nasal allergy using DSCG during the period from November 1973 to March 1974. Nasal allergy diagnostic criteria can be divided into three categories: type Ⅰ (allergic rhinitis): intradermal test and nasal induction test were positive, to determine the allergen; type Ⅱ (suspected allergic rhinitis): intradermal test positive The induced test negative; type III (the so-called vasomotor rhinitis): intradermal test negative. (All three patients had sneezing episodes, watery nose and nasal obstruction). Among the 35 cases, 23 were type Ⅰ, 5 were type Ⅱ and 7 were type Ⅲ. Medication Methods: The DSCG capsule (containing 20 mg each of DSCG and lactose) into the nasal spray, were injected into the nasal cavity, 4 times a day, continuous