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目的:了解苯二氮类药物依赖情况及依赖与有关因素的关系。方法:对符合CCMD-Ⅲ精神活性物质所致精神障碍中镇静催眠药或抗焦虑药依赖综合征的诊断标准者采用自制的调查表进行调查评估。结果:(1)女性依赖者多于男性。(2)依赖者中各种精神障碍所占的比例分别为情感性精神障碍51例(37.78%),精神分裂症42例(31.11%),躯体化障碍21例(15.56%),焦虑症12例(8.89%),癫痫3例(2.22%),失眠症3例(2.22%),酒依赖3例(2.22%)。(3)用药列为前三位的分别是劳拉西泮90例次,艾司唑仑87例次,氯硝西泮51例次。(4)首次药物的来源80%来源于医院。(5)患者知道BZ类药物会有依赖者占51.1%,但仍坚持服用该类药物的比例是78.3%。(6)医生曾经宣教过该类药物的危害占48.9%,医生宣教后继续服药者占81.8%。(7)对该类药物治疗结果满意者占86.7%。结论:该类药物的依赖女性多于男性;患者对该类药物的危害性知晓率及医生对该类药物危害性的宣教均不够;该类药物治疗效果的满意致使患者长期用药:少有的药物替代可能是依赖的一个重要的因素。
Objective: To understand the relationship between benzodiazepine drug dependence and its dependence and related factors. Methods: A self-made questionnaire was used to evaluate the diagnostic criteria of sedative-hypnotics or anti-anxiety-dependent syndromes in psychotic disorders caused by CCMD-III. Results: (1) More women than men. (2) 51% (37.78%) of affective disorders, 42 (31.11%) schizophrenia, 21 (15.56%) somatization disorders, 12 anxiety disorders Cases (8.89%), epilepsy in 3 cases (2.22%), insomnia in 3 cases (2.22%), alcohol dependence in 3 cases (2.22%). (3) Drugs listed as the top three were 90 cases of lorazepam, 87 cases of estazolam, and clonazepam 51 cases. (4) 80% of the source of the first drug comes from the hospital. (5) The patients knew that there were 51.1% of those who took BZ drugs, but still insisted on taking 78.3% of the drugs. (6) The doctors have preached the dangers of these drugs accounted for 48.9%, doctors continue to take medicine after mission accounted for 81.8%. (7) 86.7% were satisfied with the results of such drug treatment. Conclusion: The dependence of these drugs on males is more than that of males. The patients ’awareness rate of harm to these drugs and doctors’ lack of education on the dangers of these drugs are not enough. The satisfactory results of these drugs result in the long-term medication of patients: rare Drug substitution may be an important factor dependent.