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目的探讨清远地区男性不育症患者精液质量与年龄的关系。方法选取该院生殖中心男科门诊就诊的727例男性不育症患者为研究对象,依据年龄分为5组:≤25岁、>25~30岁、>30~35岁、>35~40岁、>40岁。采用计算机辅助精液分析(CASA)技术以及Diff-Quick快速染色法进行精液质量分析。结果 >30~40岁年龄段男性精液浓度较高,各年龄组间精液浓度变化没有统计学差异(P>0.05)。随着年龄的增长,前向运动(PR)精子比例、精子总活力以及精子存活率呈相对下降趋势,但各组间无明显统计学差异(P>0.05)。>25~30岁组各项精液参数指标均达到WHO标准的比例最高,占该组人数的38.19%,>40岁组比例最低,占该组人数的27.42%。结论随着年龄的增长,男性的精液质量呈下降趋势,但是不育症可发生在生育期男性的任何阶段。
Objective To investigate the relationship between semen quality and age in male infertility patients in Qingyuan area. Methods A total of 727 male infertility patients who were male clinics at the reproductive center of the hospital were enrolled in this study. The patients were divided into 5 groups according to their ages: ≤25 years,> 25 to 30 years,> 30 to 35 years,> 35 to 40 years, > 40 years old. Semen quality analysis was performed using computer-assisted semen analysis (CASA) and Diff-Quick staining. Results There was no significant difference in seminal fluid concentration between the age groups of 30-40 years old (P> 0.05). With age, the proportion of sperm in forward movement (PR), sperm motility and sperm viability decreased, but there was no significant difference between groups (P> 0.05). > Seventy-five to thirty-year-old group had the highest percentage of semen parameters reaching the WHO standard, accounting for 38.19% of the total number of the group. The lowest percentage was> 40 years old, accounting for 27.42% of the total number of the group. Conclusion With the increase of age, the sperm quality of men shows a downward trend, but infertility can occur at any stage of male fertility.