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目的:分析宫颈癌放化疗后宫颈细胞学改变特点及该项检测的临床意义。方法:采用2001年版TBS诊断系统,观察165例宫颈癌放化疗结束3个月后行544次宫颈液基薄层细胞学检查(TCT),观察细胞改变的情况并评价该检查结果与病理组织学检查结果的符合情况及临床意义。结果:受检病例544例,异常上皮细胞检出166例,阳性检出率为30.5%,其中AS-CUS,AGC,AS-CH,LSI,HSIL分别为18.5%,1.2%,2.4%,5.4%,3.0%,鳞癌和腺癌检出率为1.8%。炎症反应性细胞检出率为82.5%,其中轻、中、重度分别为7%,16.4%,9.1%。23例放疗后因细胞学检查异常进行了局部病理组织学检查,病理与TCT两者符合率为91.3%。结论:宫颈液基薄层细胞学可作为宫颈癌放化疗后局部有无复发及放射区域内生殖系统第二癌发生的初筛指标。
Objective: To analyze the characteristics of cervical cytology after radiotherapy and chemotherapy of cervical cancer and its clinical significance. Methods: The TBS diagnostic system was used in 2001, and 544 cervical cytology-based cytology tests (TCT) were performed in 165 cases of cervical cancer three months after the end of radiotherapy and chemotherapy. The changes of the cells were observed and the results were compared with histopathology Check the results of the situation and clinical significance. Results: There were 544 cases examined and 166 cases detected abnormal epithelial cells, the positive rate was 30.5%. The AS-CUS, AGC, AS-CH, LSI and HSIL were 18.5%, 1.2%, 2.4% %, 3.0%, squamous cell carcinoma and adenocarcinoma detection rate of 1.8%. The detection rate of inflammatory cells was 82.5%, among which 7%, 16.4% and 9.1% respectively. Twenty-three patients underwent local histopathological examinations due to cytology abnormalities after radiotherapy. The coincidence rate between pathology and TCT was 91.3%. Conclusion: The cervical cytology thin layer cytology can be used as cervical cancer radiotherapy and chemotherapy after the local recurrence and radiotherapy area within the first second generation of reproductive system cancer screening indicators.