病毒感染和接种是否增加多发性硬化（MS）复发的危险尚有争论。多年来疫苗制剂不断更新，但接种的安全性尚未明确。作者从临床和利增强磁共振成像（Gd-MRI）方面评价流感接种对MS病人的安全性，Gd-MRI还可确定接种后血脑屏障通透性变化是否明显。病人和方法研究对象为6例确诊MS Whether the virus infection and vaccination increases the risk of relapse from multiple sclerosis (MS) remains controversial. Vaccine formulations have been updated over the years, but the safety of vaccination is not yet known. The authors evaluated the safety of influenza vaccination in patients with MS from both clinical and MRI-enhanced magnetic resonance imaging (Gd-MRI), and Gd-MRI also determined whether changes in blood-brain barrier permeability were evident after vaccination. Patients and Methods The subjects were 6 confirmed MS