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本文以Ⅱ号复方桔皮油乳剂(含10％桔皮油和2％环己二胺四乙酸(CDTA))用于胆色素类结石溶解实验。表明:具有比其他溶石剂更强的效力,其作用与络台胆石中的钙、镁元素有关,胆石的减重率与钙元素含量下降率呈直线正相关(r=0.76,P<0.01;r=0.88,P<0.01),显示在胆石的多种金属元素中,钙是影响溶石效果的关键成份;对兔跟结膜刺激作用温和,对兔血清G.P.T、BuN、Co~(2+)均无明显影响。属较理想的溶石荆,为临床应用提供了依据。
In this paper, compound orange peel oil II (containing 10% orange oil and 2% cyclohexanediamine tetraacetic acid (CDTA)) was used for the dissolution test of bile pigments. It shows that it has stronger potency than other rock-soluble agents, and its effect is related to the calcium and magnesium elements in gallstones. The weight loss rate of gallstones is positively correlated with the decrease rate of calcium (r=0.76, P<0.01). (r=0.88, P<0.01). Among the various metallic elements in gallstones, calcium is a key component influencing the effect of litholysis; rabbits have a mild stimulation to the conjunctiva and rabbit serum GPT, BuN, and Co2+. ) No significant effect. It is an ideal dissolved stone and provides the basis for clinical application.