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目的了解重度子痫前期不同孕周对围生儿结局的影响。方法回顾性分析88例重度子痫前期患者的临床资料,按照34孕周为界分为早发型重度子痫前期组(A组)、晚发型重度子痫前期组(B组)。对其一般资料、分娩孕周、早产、胎儿生长受限发生率、新生儿窒息发生率、围生儿死亡发生率、新生儿体重等进行比较。结果①两组患者一般资料中,分娩孕周、早产发生率、规律产检率差异有统计学意义(P<0.05),其余差异均无统计学意义(P>0.05)。②围生儿结局中,各项差异均有统计学意义(P<0.05),存活新生儿中,新生儿体重比较差异也具有统计学意义(P<0.05)。结论重度子痫前期患者的发病孕周直接影响围产结局,且早发型重度子痫前期孕妇早产儿、低体重儿、围生儿死亡的发生率明显增加,相关新生儿疾病(如新生儿窒息等)的发病率也明显增加。
Objective To understand the effect of gestational age on perinatal outcome in severe preeclampsia. Methods The clinical data of 88 patients with severe preeclampsia were retrospectively analyzed. According to the 34 gestational weeks, the patients were divided into early-onset severe preeclampsia (group A) and late-onset severe preeclampsia (group B). The general information, birth gestational age, premature birth, the incidence of fetal growth restriction, the incidence of neonatal asphyxia, the incidence of perinatal death, neonatal weight were compared. Results (1) Among the general data of two groups, there were significant differences in gestational weeks, premature birth rates and regular antenatal rates between the two groups (P <0.05), while the other differences were not statistically significant (P> 0.05). (2) There was significant difference in perinatal outcome (P <0.05). There was also a statistically significant difference in body weight between surviving neonates and neonates (P <0.05). Conclusion The incidence of gestational age in patients with severe preeclampsia directly affects perinatal outcome, and the incidence of premature children, low birth weight infants and perinatal children with early-onset severe preeclampsia is significantly increased. Related neonatal diseases such as neonatal asphyxia Etc.) also significantly increased the incidence.