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目的探讨戊酸雌二醇口服用于绝经后妇女取环的临床疗效。方法 198例要求取出宫内节育器的绝经后妇女,随机分成观察组和对照组。观察组(100例)取环前口服戊酸雌二醇,对照组(98例)不做任何特殊处理,即行常规术式取环,术后均常规给与抗生素3 d口服预防感染。比较两组疗效。结果观察组顺利取出82例,取出困难17例,失败1例,术中阴道出血量<10 ml者92例,≥10 ml者8例,术后阴道出血时间(3.5±1.5)d;对照组顺利取出者23例,取出困难者60例,失败15例,术中阴道出血量<10 ml者37例,≥10 ml者61例,术后阴道出血时间(5.0±2.0)d,比较差异有统计学意义(P<0.05)。结论戊酸雌二醇用于绝经后妇女取出宫内节育器,成功率高,出血量少,便于操作。
Objective To investigate the clinical efficacy of oral administration of estradiol valerate in the postmenopausal women. Methods A total of 198 postmenopausal women who requested IUD removal were randomly divided into observation group and control group. In the observation group (100 cases), oral administration of estradiol valerate was taken before the control group (98 cases) without any special treatment. Compare the two groups curative effect. Results In the observation group, 82 cases were removed smoothly, 17 cases were removed successfully and 1 case failed. There were 92 cases of vaginal bleeding less than 10 ml, 8 cases of ≥10 ml and 3.5 ± 1.5 days after operation. The control group 23 cases were successfully removed, 60 cases were taken out of difficulty, 15 cases failed, 37 cases of intraoperative vaginal bleeding <10 ml, 61 cases of ≥ 10 ml, postoperative vaginal bleeding time (5.0 ± 2.0) d, the difference was Statistical significance (P <0.05). Conclusion Estradiol valerate is used in postmenopausal women to remove IUD. The success rate is high, the amount of bleeding is less and the operation is easy.