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硫酸乙酰肝素(Heparan Sulfate or He-paritin Sulfate)是动物组织中的一类重要物质。硫酸乙酰肝素在结构上与肝素(Heparin)有一定程度相似,都属于粘多糖类(Mucopol-ysacchardes)物质。肝素虽在临床上获得广泛的应用,但在临床上尚存在较大的付作用(如出血等),使得它的应用受到一定限制。然而,硫酸乙酰肝素在很大程度上克服了肝素应用的付作用,同时具有类似肝素的抗炎、抗血栓和降血脂等生物作用。因此,硫酸乙酰肝素是目前粘多糖中较有发展前途的新型生化药物,如国外商品Ateroid、Vessel和Asclerol是一类含
Heparan Sulfate or He-paritin Sulfate is an important class of substance in animal tissues. Heparan sulfate is structurally similar to Heparin and belongs to the class of Mucopol-ysacchardes. Although heparin has been widely used clinically, there is still a large clinical effect (such as bleeding, etc.), making its application is subject to certain restrictions. However, heparan sulfate largely overcomes the heparin effect and has biological effects such as anti-inflammatory, antithrombotic and hypolipidemic effects on heparin. Therefore, heparan sulfate is the more promising new biochemical drugs in mucopolysaccharides, such as foreign goods Ateroid, Vessel and Asclerol are a class containing