遗传性球形红细胞性溶血性贫血国内较少见,我院确诊1例,报告如下: 患者女,14岁。出生3天全身皮肤黄染,后发现左上腹有一包块,大便呈黄褐色,小便深黄色。5年来常患鼻出血,多在劳累时发生,曾多次在他院检查诊断为“黄疸型肝炎“脾亢”血吸虫病”,治疗无效。体检:发育营养欠佳,全身皮肤巩膜中度黄染,方颅、鞍鼻、贫血貌。肺部(-),各瓣膜区可闻Ⅲ级收缩期杂音,较粗糙。腹部膨隆,脾在助下18cm处可触及可移动。肝下缘在剑突下4指,助下3cm Hereditary spherocytosis hemolytic anemia less common in our hospital diagnosed in 1 case, the report is as follows: The patient female, 14 years old. Born 3 days after the body skin yellow dye, found that there is a mass of the left upper quadrant, yellowish brown stool, urine dark yellow. 5 years often suffer from nosebleeds, mostly in fatigue occurs when he repeatedly diagnosed in his hospital as “jaundice hepatitis” hypersplenism “schistosomiasis”, the treatment is invalid. Physical examination: developmental malnutrition, systemic scleral moderate yellow dye, square skull, saddle nose, anemia appearance. Lung (-), the valve area can smell Ⅲ systolic murmur, rough. Abdominal bulge, the spleen can help move 18cm office. Under the edge of the liver in the xiphoid 4 fingers, help 3cm