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目的：探讨O rem自理模式训练对精神分裂症患者服药依从性和总体幸福感的影响。方法将78例老年精神分裂症患者按随机数字表法分为观察组和对照组各39例，均予以精神科常规治疗和护理，观察组在此基础上予以O rem自理模式训练，观察8周。于训练前后采用服药依从性评定标准评定服药依从性，总体幸福感量表评定总体幸福感。结果训练前两组服药依从性、总体幸福感量表评分比较差异均无显著性（P＞0．05）；训练后观察组服药依从性评分较训练前显著降低，且显著低于对照组（P＜0．01），总体幸福感量表评分较训练前显著升高，且显著高于对照组（P＜0．01），对照组训练前后则均无显著变化（P＞0．05）。结论运用Orem自理模式训练能显著提高老年精神分裂症患者服药依从性和总体幸福感。“,”Objective To explore the influence of Orem’s self‐care model‐based training (OSCMBT ) on medication compliance and general well‐being of schizophrenic .Methods Seventy‐eight elderly schizo‐phrenics were assigned to observation and control group of 39 ones each according to random number table , both groups received routine psychiatric treatment and nursing ,on this basis observation group was plus the OSCMBT for 8 weeks .Medication compliances were assessed using medication compliance assessment criteria and general well‐beings with the General Well‐being Schedule (GWB) before and after training . Results There were no significant group differences in medication compliance and the GWP scores before training (P>0 .05);after training medication compliance score lowered more significantly in observation group and was significantly lower than in control group (P<0 .01) and general well‐being heightened and higher (P0 .05) .Conclusion The OSCMBT could notably boost the medication compliance and general well‐being of senile schizophrenics .