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·—333 组织因子(TF)可存在于循环血浆中,为弄清其临床意义,用酶联免疫吸附法检测了65例弥散性血管内凝血(DIC)患者的血浆TF,其中急性早幼粒细胞白血病4例,急性髓细胞白血病14例,急性淋巴细胞白血病5例,慢粒急变8例,恶性淋巴瘤4例,实体瘤11例,感染7例,血管损伤3例,其它疾病9例。30名正常人作对照。结果:①DIC患者组血浆TF较正常对照组增高(446±SD536pg/ml,138±51pg/ml,P<0.001),在DIC组超过正常值上限的
Tissue factor (TF) may exist in the circulating plasma, in order to clarify its clinical significance, enzyme-linked immunosorbent assay was used in 65 cases of diffuse intravascular coagulation (DIC) in patients with plasma TF, in which acute promyelocytic 4 cases of cell leukemia, acute myeloid leukemia in 14 cases, 5 cases of acute lymphoblastic leukemia, 8 cases of acute myeloid leukemia, 4 cases of malignant lymphoma, solid tumors in 11 cases, 7 cases of infection, vascular injury in 3 cases, 9 cases of other diseases. 30 normal people as a control. Results: (1) Plasma TF in patients with DIC was significantly higher than that in controls (446 ± SD536pg / ml, 138 ± 51pg / ml, P <0.001)