灼口综合征(BMS)是临床较常见的疾病,其病因不明,但精神心理及神经因素占突出地位。对病因的研究有助于提高该病的临床治愈率,以减轻患者痛苦。近年来国内外关于精神心理及神经因素在BMS中的研究较多。该文就BMS的精神心理因素、中枢神经因素、周围神经因素、分子机制等方面的研究进展进行论述。 Burning mouth syndrome (BMS) is a more common clinical disease, the etiology is unknown, but the psychological and neurological factors play a prominent role. The study of the cause of the disease helps to improve the clinical cure rate of the disease, in order to reduce the suffering of patients. In recent years, there are many researches on mental psychology and neurological factors in BMS at home and abroad. This article discusses the research progress of mental health factors, central nervous system factors, peripheral nerve factors and molecular mechanisms of BMS.