苯是工业上广泛使用的一种溶剂,但人们对其代谢和代谢与其毒性关系仍不完全了解。过去研究表明,苯必须经肝脏代谢后产生毒作用。苯主要的代谢产物是酚、氢醌和邻苯二酚。尽管骨髓是苯毒性的靶部位,但引起骨髓毒性的苯代谢产物至今仍不清楚。近来报道,用苯处理大鼠后,骨髓脂类过氧化反应增强,并 Benzene is a widely used solvent in industry, but people still do not fully understand the relationship between its metabolism and metabolism and its toxicity. Past studies have shown that benzene must be metabolized by the liver toxic effects. The main metabolites of benzene are phenol, hydroquinone and catechol. Although bone marrow is the target of benign toxicity, the benzene metabolites that cause myelotoxicity are still unknown. It has recently been reported that with benzene treatment of rats, myeloperoxidation is enhanced and