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作者应用固相酶免疫测定法对HBV感染患者血清进行前S_1和前S_2抗原的定量分析,并观察其滴度与HBsAg滴度以及其他HBV标志的关系。急性乙型肝炎时前S_1和前S_2抗原的检测:作者观察了3例急性肝炎患者前S抗原的变化,1例患者在转氨酶升高前入院,在首次血标本中查见前S_1、前S_2抗原和HBsAg。同时HBeAg、HBV DNAP和HBV DNA也阳性。此后,前S_1和前S_2抗原以及HBsAg滴度下降。当HBV DNAP和HBV DNA消失后,ALT达到高峰时,
The authors apply the enzyme immunoassay of solid phase enzyme immunoassay in patients with serum HBV pre-S 1 and S 2 antigen quantitative analysis and observe the titer and HBsAg titers and other HBV markers. Detection of pre-S 1 and pre-S 2 antigens in acute hepatitis B: The authors observed the changes in pre-S antigen in 3 patients with acute hepatitis and one patient was hospitalized before transaminases were elevated. The first S 1, the former S 2 Antigen and HBsAg. At the same time, HBeAg, HBV DNAP and HBV DNA are also positive. Thereafter, the pre-S 1 and pre-S 2 antigens and the HBsAg titer decreased. When HBV DNAP and HBV DNA disappeared, ALT reached its peak,