我们从1980年12月至1986年4月曾治疗5例,现将随访到的3例报告如下。病例简介例1,男,5岁7个月。患儿3岁起行走乏力,下肢呈O形腿,渐加重。曾口服鱼肝油、钙片及多种维生素治疗无效。入院体检:营养发育差,身高82cm,体重14kg,智力正常;方颅I°,乳牙脱落9颗、鸡胸Ⅱ°、肋串珠Ⅱ°、赫氏沟Ⅱ°、脊柱后突I°、手镯症Ⅲ°、脚镯症Ⅲ°,O形腿Ⅲ°,四肢肌力、肌张力正常。化验检查;血钙8.1～9mg/dl,血磷2.4～5.5mg/dl,尿钙180～290mg/24小时、尿磷1.4～1.9g/24小时,AKP35～50金氏单位。血钾、钠、氯、二氧化碳结合力、尿素氮、肝功能均正常。骨X线检查呈佝偻病激期改变。诊断为低血磷性抗维生素D性佝偻病。用大剂量维 We have treated 5 cases from December 1980 to April 1986, and the 3 cases we will follow are as follows. Case description Example 1, male, 5 years and 7 months. 3-year-old children starting walking fatigue, lower limbs were O-shaped legs, gradually heavier. Had oral cod liver oil, calcium and vitamins treatment ineffective. Admission physical examination: poor nutrition, height 82cm, weight 14kg, normal intelligence; square cranial I °, deciduous teeth 9, Ⅱ × chest, ribs Bertha Ⅱ Ⅱ, Herniated groove Ⅱ °, posterior spinal column I °, Bracelet Ⅲ °, ankle disease Ⅲ °, O-leg Ⅲ °, limb muscle strength, muscle tone normal. Laboratory tests; serum calcium 8.1 ~ 9mg / dl, phosphorus 2.4 ~ 5.5mg / dl, urinary calcium 180 ~ 290mg / 24 hours, urinary phosphorus 1.4 ~ 1.9g / 24 hours, AKP 35 ~ 50 gold units. Potassium, sodium, chlorine, carbon dioxide binding, urea nitrogen, liver function are normal. Bone X-ray examination showed rickets changes in the early stage. Diagnosis of hypophosphatemic anti-vitamin D rickets. Use large doses of dimension