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目的观察分析噻托溴铵联合沙美特罗替卡松(舒利迭)治疗慢性阻塞性肺疾病的临床效果。方法 56例慢性阻塞性肺疾病患者,将其随机分成对照组与研究组两组,每组28例,给予对照组采用舒利迭治疗,给予研究组在对照组的基础上加用噻托溴铵治疗,比较两组治疗效果。结果通过治疗1个月以后,两组患者的肺功能各项指标均有不同程度的改善,差异有统计学意义(P<0.05)。其中研究组FEV1与FEV1/FVC两项指标的变化更明显,差异有统计学意义(P<0.05)。结论噻托溴铵联合舒利迭治疗慢性阻塞性肺病患者,能够有效改善其肺功能,值得临床推广应用。
Objective To observe the clinical effect of tiotropium combined with salmeterol and fluticasone (seretide) on chronic obstructive pulmonary disease. Methods Fifty-six patients with chronic obstructive pulmonary disease were randomly divided into two groups: control group and study group, with 28 cases in each group. Patients in control group were treated with seretide. The patients in study group were treated with tiotropium Ammonium treatment, the two groups were compared. Results After one month of treatment, the indexes of pulmonary function in both groups improved to some extent, the difference was statistically significant (P <0.05). The changes of FEV1 and FEV1 / FVC in the study group were more obvious, the difference was statistically significant (P <0.05). Conclusion tiotropium combined with seretide in patients with chronic obstructive pulmonary disease, can effectively improve their lung function, it is worth promoting the clinical application.