自本世纪中叶发现B 细胞能够合成并分泌免疫球蛋白(Ig)以来,一般认为B 细胞的功能就是产生抗体。70年代起出现了关于B 细胞免疫调节功能的报道,近年来这方面的研究逐渐增多,发现B 细胞也是参与免疫调节的细胞。一、B 细胞的免疫调节功能1.提呈抗原和分泌白细胞介素1(IL-1)抗原激活T 细胞,需要抗原提呈细胞(APC)的参与。一般认为单核巨噬细胞(Mφ)、树突状细胞和朗格罕氏细胞等具 Since the discovery of B cells in the middle of this century to synthesize and secrete immunoglobulin (Ig), it is generally believed that the function of B cells is to produce antibodies. Since the 1970s, there have been reports on the immunoregulatory function of B cells. In recent years, there has been a growing number of studies showing that B cells are also involved in immune regulation. First, the immune function of B cells 1. Antigen presentation and secretion of interleukin 1 (IL-1) antigen-activated T cells, the need for antigen-presenting cells (APC) involved. Generally believed that mononuclear macrophages (Mφ), dendritic cells and Langerhans cells and so on