目前,癌肿治疗的最佳方案是综合治疗.即外科手术、放疗、化疗以及生物治疗等的有机配合.某些肿瘤往往需要放疗、化疗或者放化疗相结合的方案。例如 ,鼻咽癌、血液系统的恶性肿瘤。在多数的情况下,放疗、化疗是配合手术进行的。但是上述治疗方法均存在着优缺点,全身各系统(包括口腔颌面部)的放、化疗,由于缺乏其作用的选择性.而致损伤人体的正常组织器官.产生并发症(包括口腔内)。往往造成治疗中断或影响病人的生存质量,严重的并发症甚至影响生命。因此,诊断、治疗、预防这些并发症不仅是口腔医师的职责,而且对临床各种特别是肿瘤专家、放射科的医师所应该共识的。 一、放、化疗引起口腔并发症的细胞生物学的基础 At present, the best solution for cancer treatment is combination therapy, which is the organic combination of surgery, radiotherapy, chemotherapy and biotherapy, etc. Some tumors often require a combination of radiotherapy, chemotherapy or radiotherapy and chemotherapy. For example, nasopharyngeal cancer, a hematological malignancy. In most cases, radiotherapy and chemotherapy are performed in conjunction with surgery. However, there are advantages and disadvantages of the above treatment methods. The systemic and systemic (including oral and maxillofacial) radiotherapy and chemotherapy, due to the lack of selectivity, cause damage to the normal tissues and organs of the human body. Complications (including the oral cavity) . Often caused by treatment interruption or affect the quality of life of patients, serious complications and even affect their lives. Therefore, the diagnosis, treatment and prevention of these complications are not only the responsibility of the dentist, but also should be agreed to by all kinds of clinical specialists, especially oncologists and radiologists. First, radiotherapy and chemotherapy caused by oral complications of cell biology