1例48岁女性患者因记忆力下降口服复方苁蓉益智胶囊1.2 g（4粒），3次/d。约20 d后，患者出现恶心，纳差，尿黄和皮肤、巩膜黄染。停用复方苁蓉益智胶囊。停药7 d后，实验室检查：丙氨酸转氨酶（ALT）1 349 U/L，天冬氨酸转氨酶（AST）827 U/L，碱性磷酸酶（ALP）156 U/L，总胆红素（TBil）213.7 μmol/L，考虑为复方苁蓉益智胶囊致肝损伤。给予还原型谷胱甘肽、复方甘草酸苷、丁二磺酸腺苷蛋氨酸、地塞米松等药物治疗。患者食欲逐渐改善，黄疸逐渐消退。治疗36 d后复查：ALT 26 U/L，AST 30U/L，ALP 86U/L，TBil 27.2 μmol/L。考虑患者的肝损伤与复方苁蓉益智胶囊中的制何首乌有关。“,”A 48-year-old female patient received compound n Congrong Yizhi capsules 1.2 g (4 capsules) orally thrice daily for memory decline. About 20 days later, the patient developed nausea, anorexia, yellow urine, and yellow staining of skin and sclera. Compound n Congrong Yizhi capsules were discontinued. Seven days after drug withdrawal, laboratory tests showed that alanine aminotransferase (ALT) was 1 349 U/L, aspartate aminotransferase (AST) was 827 U/L, alkaline phosphatase (ALP) was 156 U/L, and total bilirubin (TBil) was 213.7 μmol/L. Liver injury induced by compound n Congrong Yizhi capsules was considered. Reduced glutathione, compound glycyrrhizin, ademetionine 1,4-butanedisulfonate, and dexamethasone were given. The patient′s appetite was gradually improved and jaundice gradually subsided. After 36 days of treatments, ALT was 26 U/L, AST was 30 U/L, ALP was 86 U/L, and TBil was 27.2 μmol/L. The liver injury of the patient was considered to be related to n Radix Polygoni Multiflori Preparata (prepared fleeceflower root) in compound n Congrong Yizhi capsules.n