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本文旨在研究限钠和/或高钾饮食对有或无高血压家族史的血压正常者的作用。受试者为20名血压正常的男性医学生,年龄为21~25岁。10名有高血压家族史,其余10名已知其上2代血压均属正常。随机给予受试者试验饮食~*,每种饮食均用2周,热卡摄入不变。结果适当限钠或单独高钾饮食使体重减轻约1kg,同时血清肌酐和尿酸轻度而有意义的增加。5名测量钠池者,低钠/高钾饮食使钠从25.75±1.79(±SEM)降至21.83±1.24L(P<0.005)。各种饮食无明显血钾变化,但血清钠增高,肾素-醛固酮系统的最大刺激发生在低钠/高钾摄入以后,与单独低钠或高钾摄入相比,此期间尿钠排出较少,而尿钾排
This article aims to investigate the effects of sodium-limiting and / or potassium-rich diets on normotensive individuals with or without a family history of hypertension. Subjects were 20 normal male medical students, aged 21 to 25 years old. 10 had a family history of hypertension, the other 10 known to be on the 2nd generation of blood pressure are normal. Subjects were randomly assigned to a trial diet of ~ *, each diet for 2 weeks, calorie intake unchanged. Results Appropriate sodium restriction alone or high potassium diet to lose about 1kg weight, while serum creatinine and uric acid slightly and meaningful increase. Of the five sodium pool gauges, sodium decreased from 25.75 ± 1.79 (± SEM) to 21.83 ± 1.24L (P <0.005) for the sodium / potassium diet. No significant changes in serum potassium levels, but serum sodium increased, the maximum stimulation of the renin - aldosterone system occurred in the sodium / potassium intake, compared with the intake of sodium alone or low compared to sodium urinary sodium excretion Less, while urine potassium row