感染是导致慢性阻塞性肺疾病 (COPD)急性发作及病情加重的重要原因。为探讨 COPD急性加重期细菌感染状况及其与肺功能下降的关系 ,我们对 2 6 2例 COPD急性加重期患者行痰细菌培养 ,并对其中 191例痰菌阳性患者行肺功能检测 ,现报告如下。资料与方法 :观察对象为 2 6 2例 COPD Infection is the leading cause of acute exacerbation and exacerbation of chronic obstructive pulmonary disease (COPD). In order to investigate the relationship between bacterial infection and pulmonary function decline in acute exacerbation of COPD, we conducted sputum bacterial culture in 262 patients with acute exacerbation of COPD and detected pulmonary function in 191 sputum positive patients as follows. Materials and Methods: The subjects were 2662 COPD patients