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本文报道用改良简化法和计算公式测定180例正常人和120例慢性阻塞性肺部疾病患者的平均通过时间,以及反映小气道功能的部分平均通过时间。求出了与年龄相关的直线回归方程,分析了平均通过时间、反映小气道功能的部分平均通过时间的影响因素和临床意义。初步认为平均通过时间和反映小气道功能的部分平均通过时间是检测小气过阻塞敏感的肺功能指标。
This paper reports the mean transit time of 180 normal subjects and 120 patients with chronic obstructive pulmonary disease measured by the improved simplified method and the calculation formula, and the partial mean transit time reflecting the function of small airways. The age-related linear regression equation was obtained, and the influencing factors and clinical significance of mean transit time and partial mean transit time of small airway function were analyzed. The mean transit time and partial mean transit time, which reflect the function of small airways, are preliminarily considered as indicators of pulmonary function that are sensitive to the detection of paroxysmal airway obstruction.