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反流性食管炎是由于胃或肠内容物反流入食管,引起食管下段粘膜的炎症,其原因主要是由于食管下端括约肌(LES)功能减弱,当胃内压力增高时,括约肌的压力不能随之增高,出现胃肠内容物反流入食管。日常生活中饮酒、吸烟、反复呕吐、插胃管、胃潴留、十二指肠溃疡、阿托品、迷走神经切断术等都可使LES的功能减弱,引起胃肠内容物反流到食管。而食管的蠕动功能障碍,使反流物在食管内滞留较久则是食管炎持续存在的因素之一。食管炎反过来又可累及LES,
Reflux esophagitis is due to reflux of the stomach or intestinal contents into the esophagus, causing inflammation of the lower esophageal mucosa, mainly due to decreased function of the lower esophageal sphincter (LES), when the intragastric pressure, sphincter pressure can not follow Increased, there gastrointestinal reflux into the esophagus. Daily life, drinking, smoking, repeated vomiting, gastric tube insertion, gastric retention, duodenal ulcer, atropine, vagotomy and other functions can make LES weakened, causing reflux of gastrointestinal contents to the esophagus. The peristalsis of esophageal dysfunction, so that reflux in the esophagus for more than a long stay is one of the factors that continue the existence of esophagitis. Esophagitis in turn can affect LES,