盐酸甲苄肼为 N-甲肼的衍生物,常用于治疗何杰金氏病。本文介绍测定盐酸甲苄肼的精确、灵敏和具有选择性的方法,是基于用0.1N 硫酸铈(Ⅳ)铵氧化该药品,生成甲醛和4-甲酰基-N-异丙基苯甲酰胺。后者可生成其衍生物2,4-二硝基苯腙而分离;再用氢氧化钾乙醇溶液处理,呈现红色,在λ_(max)= Benzylhydrazine hydrochloride is a derivative of N-methylhydrazine, commonly used in the treatment of Hodgkin’s disease. This paper presents an accurate, sensitive, and selective method for the determination of procarbazine hydrochloride based on the oxidation of this drug with 0.1 N ammonium cerium (IV) sulfate to form formaldehyde and 4-formyl-N-isopropylbenzamide. The latter can generate derivatives of 2,4 - dinitrophenylhydrazone and separation; and then treated with ethanol solution of potassium hydroxide, showing red, λ_ (max) =