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[目的]探讨早期子宫内膜癌患者保留生育功能治疗的适应证、治疗方法和安全性.[方法]对2006年1月至2010年3月接受保留生育功能治疗的3例早期子宫内膜癌患者,回顾性分析其临床资料、诊疗经过、近期疗效及妊娠结局.[结果]3例患者年龄分别为25岁、27岁、32岁,均为高分化子宫内膜样腺癌,雌、孕激素受体均阳性给予高效孕激素为主的药物治疗 . 3例患者初始治疗3~6个月内均获完全缓解,1例复发后重复3次药物治疗获得完全缓解、1例停药后8周复发,病理升级为分化差的癌而终止保守治疗.其中2例患者分别于治疗结束后第7、11个月妊娠,其新生儿均健康.[结论]严格掌握适应证的前提下对年轻且有强烈生育愿望的早期子宫内膜癌患者实施保留生育功能治疗是安全可行的,肿瘤控制后应尽早辅助生育,完成生育后进行全面评估,密切随访.“,”Objective] To explore the indications ,treatment protocols and safety of fertility‐sparing treat‐ment for early endometrial carcinoma .[Methods] Clinical data ,diagnosis process ,short‐term efficacy and pregnant outcome of 3 patients with early endometrial carcinoma receiving fertility‐sparing treatment from Jan . 2006 to March 2010 were analyzed retrospectively .[Results] Three patients were given drug therapy mainly including high effective progestogen .The age of 3 patients were 25 ,27 and 32 years old ,respectively .All pa‐tients were well‐differentiated endometrial carcinoma with positive estrogen and progestogen receptors .After 3~ 6 months of initial therapy ,3 patients got complete remission .One patient recurred ,and then got complete remission after repetitive drug therapy for 3 times .One patient relapsed after drug withdrawal for 8 weeks and then stopped the conservation therapy for developing into poor‐differentiated carcinoma .Two patients were pregnant at 7 and 11 months in the end of treatment ,respectively .All neonates were healthy .[Conclusion]On the basis of strictly controlling the indications ,fertility‐sparing treatment for young patients with endome‐trial carcinoma who have strong desire for reproduction is safe and feasible .After the tumor control ,the assis‐ted reproduction should be undertaken as soon as possible .The overall evaluation should be preformed after the childbearing ,and the close follow‐up should be taken .