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目的:探讨苯甲酸雌二醇序贯法配合中药汤剂治疗脾肾亏虚型青春期功能性子宫出血的临床疗效。方法:将200例青春期功能性子宫出血患者随机分为2组各100例,对照组予苯甲酸雌二醇序贯治疗,治疗组则在对照组基础上加用补肾健脾中药汤剂口服,疗程结束后比较2组患者出血控制时间及出血停止时间,出血复发情况及不良反应发生情况,并评价临床疗效。结果:总有效率治疗组为95.0%,对照组为82.0%,2组比较,差异有统计学意义(P<0.05)。治疗组出血控制时间及出血停止时间均明显较对照组缩短,差异有统计学意义(P<0.05)。复发率、不良反应发生率治疗组分别为3.0%、5.0%,对照组分别为11.0%、21.0%,2组比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗脾肾亏虚型青春期功能性子宫出血能明显缩短出血时间,减少不良反应及复发率,恢复月经周期。
Objective: To investigate the clinical efficacy of benzoic acid sequential injection of estradiol in combination with traditional Chinese medicine decoction in the treatment of adolescent dysfunctional uterine bleeding in spleen and kidney deficiency type. Methods: 200 cases of adolescent dysfunctional uterine bleeding were randomly divided into two groups of 100 cases, the control group to sequential treatment of estradiol benzoate, the treatment group is based on the control group with the Bushen Jianpi decoction oral, After the course of treatment, the bleeding control time, the stopping time of bleeding, the recurrence of bleeding and the incidence of adverse reactions were compared between the two groups, and the clinical efficacy was evaluated. Results: The total effective rate was 95.0% in the treatment group and 82.0% in the control group. There was significant difference between the two groups (P <0.05). The bleeding time and the stopping time of bleeding in the treatment group were significantly shorter than those in the control group, with significant difference (P <0.05). The incidences of recurrence and adverse reactions in the treatment group were 3.0% and 5.0%, respectively, while those in the control group were 11.0% and 21.0% respectively. There was significant difference between the two groups (P <0.05). Conclusion: Integrative Chinese and Western medicine treatment of spleen and kidney dysfunctional adolescent dysfunctional uterine bleeding can significantly reduce the bleeding time, reduce adverse reactions and recurrence rate, restore menstrual cycle.