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HDV核酶为HDV双滚环复制所必需,最小序列约85核苷酸(nt)左右,呈独持的假结样结构,其结构和功能的关系已得到深入探索。反式HDV核酶可能会成为一种新型有效的抗病毒药物。
HDV ribozyme is required for HDV double-circle replication. The minimum length of HDV ribozyme is about 85 nucleotides (nt), which is a unique pseudoknot-like structure. The relationship between structure and function has been explored. Trans-HDV ribozymes may become a new and effective antiviral drug.