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西咪替丁是一种强有力的组织胺H2受体阻断剂,能选择性地阻断胃壁细胞的H2受体,抵抗组织胺或其他因素引起的胃酸分泌,从而使胃粘膜毛细血管的通透性降低,有利于消除胃粘膜充血水肿,减少胃酸分泌,同时还能控制胃蛋白酶分泌并使其活性降低,有利于粘膜屏障的重建和出血的控制,促进溃疡愈合[1]。
Cimetidine is a potent histamine H2 receptor blocker that selectively blocks the H2 receptors in gastric parietal cells against the secretion of gastric acid by histamine or other factors that cause the mucosal capillary Lower permeability, is conducive to the elimination of gastric mucosal congestion and edema, reduce gastric acid secretion, but also control the secretion of pepsin and its activity is reduced, is conducive to mucosal barrier reconstruction and bleeding control, and promote ulcer healing [1].