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化淤灵是根据中医活血化淤的理论研制的注射液,我们首先进行了实验性血栓形成,减压缺氧耐力、血流变学、血小板聚集功能、环核苷酸、纤溶活性、冠脉流量、心率、镇痛、肝肾功能及半数致死量11项动物实验,证明化淤灵通过改变血液流变学改善微循环,抑制血小板的聚集功能。提高cAMP,降低cGMP的水平,缩短ELT促进纤溶活性和兴奋β_2-受体的作用机制,达到抑制血栓形成,增加冠脉流量,抗减压缺氧和镇痛的作用。
Siltification is an injection developed according to the theory of traditional Chinese medicine promoting blood circulation. We first performed experimental thrombosis, decompression and hypoxia tolerance, blood rheology, platelet aggregation, cyclic nucleotides, fibrinolysis activity, and crown. Pulsed blood flow, heart rate, analgesia, liver and kidney function, and median lethal doses in 11 animal experiments have shown that Hualingling can improve microcirculation and inhibit platelet aggregation by altering hemorheology. Improve cAMP, reduce the level of cGMP, shorten the action mechanism of ELT to promote fibrinolysis and excitement of β 2 -receptors, achieve inhibition of thrombosis, increase coronary blood flow, anti-decompression, hypoxia and analgesia.