论文部分内容阅读
目的:探讨孕早期微量元素变化与妊娠不良结局的相关性。方法:研究组219例,包括孕早期先兆流产、流产及胚胎停止发育的孕妇;对照组134例,包括正常孕早期56例和未孕78例妇女。分别测各组微量元素铅(Pb)、镉(Cd)、铁(Fe)、铜(Cu)、锌(Zn)水平。结果:对照组中正常早孕与未孕组比较:Pb、Cd差异无统计学意义(P>0.05);Fe、Cu显著升高,差异有统计学意义(P<0.05);Zn显著降低,差异有统计学意义(P<0.05)。研究组与对照组中正常早孕者比较:Pb、Cd无明显变化(P>0.05);Fe、Cu、Zn下降明显,差异有统计学意义(P<0.05)。结论:铁、锌、铜等是孕早期关键性微量元素,在孕早期严重缺乏可致先兆流产、流产及胚胎停止发育,因此孕早期孕妇应注意摄入含Fe、Zn、Cu等丰富的食物,避免孕早期不良妊娠结局的发生。
Objective: To explore the correlation between the changes of trace elements in early pregnancy and poor outcome of pregnancy. Methods: The study group consisted of 219 pregnant women, including pregnant women with threatened abortion, abortion and embryo development during the first trimester. The control group consisted of 134 pregnant women, including 56 normal pregnant women and 78 nonpregnant women. The levels of Pb, Cd, Fe, Cu and Zn in each group were measured. Results: There was no significant difference in Pb and Cd between the normal pregnancy group and the non-pregnant group in the control group (P> 0.05), Fe and Cu were significantly increased (P <0.05), while Zn was significantly lower There was statistical significance (P <0.05). There were no significant changes in Pb and Cd (P> 0.05) between the study group and the control group. The levels of Fe, Cu and Zn decreased significantly (P <0.05). Conclusion: Iron, zinc and copper are the key trace elements in early pregnancy. Serious lack of early pregnancy may lead to threatened abortion, abortion and the development of embryos. Therefore, expectant mothers should pay attention to the intake of foods rich in Fe, Zn and Cu during early pregnancy , To avoid the occurrence of adverse pregnancy outcomes in early pregnancy.