神经皮肤黑色素瘤综合征恶变一例邹积典郭庆雷＊郭文斌患者，男，２２岁。出生时全身散在分布大小不等黑色斑，其上有黑色毳毛，随年龄增长皮损不断扩大，并粗糙肥厚，毳毛变粗，变长。于出生后３个月、１０个月两次无明原因抽搐发作，在当地医院给予抗癫痫治疗好转。１... A case of malignant transformation of neurocutaneous melanoma syndrome Zou Jidian, Guo Qinglei, Guo Wenbin, male, 22 years old. At birth, the body was scattered in black spots of varying sizes, with black bristles on it, and with the increase of age, the skin lesions continued to expand, and rough and thick, and the bristles became thicker and longer. Three episodes of unexplained seizures occurred 3 months and 10 months after birth, and anti-epileptic treatment was improved in local hospitals. 1...