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系统性红斑狼疮(SLE)合并神经系统损害的神经精神性红斑狼疮(NP-SLE)已有报道今报告一对孪生姊妹同患NP-SLE如下。 例1 女,13岁,3年前无诱因发热(38～39℃)1周,继而面部出现蝶形红斑、双眼睑水肿、心悸,抗核抗体及狼疮细胞均阳性,诊断SLE。两次住院,长期口服激素。一个月前再现高热,随即发生四肢抽搐、双眼上翻、面色青紫、口吐白沫、二便失禁,每次发作持续2～3分钟,发作5次后于1993年2月15日住院。查体:满月脸,向心性肥胖,心肺腹未发现异常。神经科检查:神志清,不全性混合性失语,颅神经无异常。右侧肢体
Systemic lupus erythematosus (SLE) with neurological impairment Neuropsychiatric lupus erythematosus (NP-SLE) It has been reported that a pair of twin sisters with NP-SLE are reported below. Case 1 Female, 13 years old, 3 years ago, no incentive fever (38 ~ 39 ℃) for 1 week, followed by facial butterfly erythema, double eyelid edema, palpitations, antinuclear antibodies and lupus cells were positive diagnosis of SLE. Hospitalized twice, long-term oral hormones. Reproductive fever a month ago, followed by limbs twitching, eyes upturned, looking bruising, foaming at the mouth, second incontinence, each episode lasts 2 to 3 minutes, 5 episodes after February 15, 1993 hospital. Physical examination: full moon face, concentric obesity, cardiopulmonary abdominal found no abnormalities. Neurological examination: Conscious, incomplete mixed aphasia, cranial nerves without exception. Right limb