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喹哌为一长效口服抗疟药和矽肺防治药物,我们观察了~(14)C标记的磷酸喹哌(~(14)C-PQP)和喹哌硷基(~(14)C-QP)二种制剂在动物体内的代谢过程,以便为临床合理用药和新药研究提供参考。本实验着重观察磷酸喹哌一次口服用药后一个月内的吸收、分布和排泄;同时比较了喹哌
Quipiper is a long-acting oral antimalarial drug and silicosis prevention and treatment drug. We observed the effect of ~ (14) C-labeled quipiperazine (~ (14) C-PQP) and quinpirine (~ (14) C-QP ) Two kinds of preparations in animal metabolism in order to provide a reference for the clinical rational use of drugs and new drug research. This experiment focused on the observation of a single oral administration of quinpiripete within one month after absorption, distribution and excretion; at the same time compared the Quiper