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蛋白激酶家族参与多种关键的细胞周期功能的调节,对细胞DNA损伤、修复及重组起调控作用。磷脂酰肌醇3激酶(phosphatidylinositol-3-kinase,PI3k)和Akt(蛋白激酶B)参与的信号通路在信号传导上起重要作用,可活化一系列其他的激酶链。哺乳动物雷帕霉素靶蛋白(mammaliantargetofrap
The protein kinase family is involved in the regulation of many key cell cycle functions and plays a regulatory role in cell DNA damage, repair and reorganization. The signaling pathways involved in phosphatidylinositol-3-kinase (PI3k) and Akt (protein kinase B) play an important role in signaling and can activate a range of other kinase chains. Mammalian rapamycin target protein (mammaliantargetofrap