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结核性脑膜炎(简称结脑)的死亡率仍然是很高的,除非能早期诊断和及时治疗,在治疗期间或完成治疗后出现神经系后遗症的病人,仍占有较大比例。本文对所有病人在出院后四年半以上的情况作了回顾性调查。病人年龄在1～12岁之间,均用三种方案中之一种作过治疗。三种方案的第一阶段含链霉素、异烟肼每日及利福平每日或每周二次服用,头两个月每日服用吡嗪酰胺(Pyfazinamide)或者不用;第二阶段含异烟肼、乙胺丁醇每日服用10个月,每周两次应用链霉素或者不用。三种方案结果相似,33%的病人从脑脊液中分离结核分支杆菌。
The mortality rate of tuberculous meningitis (tuberculous meningitis) is still very high, unless early diagnosis and timely treatment, during treatment or after treatment of patients with neurological sequelae still occupy a large proportion. This article retrospectively examined the status of all patients after discharge for more than four and a half years. Patients aged 1 to 12 years old, were treated with one of three options. The first of three regimens contains streptomycin, isoniazid daily and rifampin twice daily or twice weekly for the first two months with or without Pyfazinamide, and the second phase contains Hydrazide, Ethambutol Daily take 10 months, twice weekly application of streptomycin or not. The results for the three protocols were similar, with 33% of patients isolating M. tuberculosis from cerebrospinal fluid.