砷是自然界分布极广的有毒的类金属元素。有关砷与人体健康以及砷的致癌机制 ,已成为各国学者关注的热点。就近年来有关砷的研究资料 ,从砷的暴露及毒性、砷的代谢、砷的流行病学以及生物动力学、剂量效应和砷致癌的分子机制等六个方面加以综述 ,阐述砷对健康的毒性影响 ,并提出今后的主要研究方向。 Arsenic is a naturally occurring type of toxic metalloid element. Concerning the arsenic and human health and the carcinogenic mechanism of arsenic, it has become a hot spot for scholars from all over the world. In recent years, arsenic research data, from the arsenic exposure and toxicity, arsenic metabolism, arsenic epidemiology and biodynamics, dose effects and molecular mechanisms of arsenic carcinogen were reviewed six aspects of the health of arsenic toxicity Influence, and put forward the main research direction in the future.